RNA and protein evolution Molecular engineering

Our laboratory started in June 2022.
We aim to research the origin of life and develop new biotechnology, by evolving RNA and proteins in the laboratory

Virus origin

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News & Events

A preprint about Polymorphic Structures of an Artificial Nucleocapsid Evolved from a Circularly Permuted Bacterial Protein Cage has been posted on bioRxiv

3 days ago

One doctoral course student have joined us!

Oct 6

A co-authored paper on a cell-free protein expression system from extremely low DNA concentrations has been published in the journal ACS Synthetic Biology.

Sep 7

A paper regarding on N-terminal incorporation of ncAA has been published in ACS Synthetic Biology

Sep 7

Dr. Masahiro Noji has received the Young Scientist Award from the Protein Science Society of Japan!

Jul 2

Graduate student Mr. Shohei Ito won a poster award at DROPLET2026!

Jun 30

A paper regarding on in vitro assembly of split nucleocapsids has been published in ACS Synthetic Biology

May 28

A preprint about a method for introducing unnatural amino acids to the N-terminus of proteins and de novo binder screening has been posted on bioRxiv

May 28

A paper regarding on an engineered closed-shell, two-component, 480-subunit nucleocapsid has been published in PNAS

May 28

Two preprints on protein evolution using cell-free translation systems have been posted on bioRxiv.

Feb 24

Two preprints on artificial nucleocapsids have been posted on bioRxiv.

Jan 4

A paper regarding on artificial nucleocapsids for RNA delivery has been published in Angewandte Chemie

Jan 4

2 3

Earth-Life Science Institute Institute of Future Science, Institute of Science Tokyo

RNA and protein evolution Molecular engineering

News & Events

A preprint about Polymorphic Structures of an Artificial Nucleocapsid Evolved from a Circularly Permuted Bacterial Protein Cage has been posted on bioRxiv

One doctoral course student have joined us!

A co-authored paper on a cell-free protein expression system from extremely low DNA concentrations has been published in the journal ACS Synthetic Biology.

A paper regarding on N-terminal incorporation of ncAA has been published in ACS Synthetic Biology

Dr. Masahiro Noji has received the Young Scientist Award from the Protein Science Society of Japan!

Graduate student Mr. Shohei Ito won a poster award at DROPLET2026!

A paper regarding on in vitro assembly of split nucleocapsids has been published in ACS Synthetic Biology

A preprint about a method for introducing unnatural amino acids to the N-terminus of proteins and de novo binder screening has been posted on bioRxiv

A paper regarding on an engineered closed-shell, two-component, 480-subunit nucleocapsid has been published in PNAS

Two preprints on protein evolution using cell-free translation systems have been posted on bioRxiv.

Two preprints on artificial nucleocapsids have been posted on bioRxiv.

A paper regarding on artificial nucleocapsids for RNA delivery has been published in Angewandte Chemie

Earth-Life Science Institute
Institute of Future Science, Institute of Science Tokyo